Colts coach Chuck Pagano scored his 13th career victory against the Buffalo Bills and snapped the Bills’ four-game winning streak in the process.
With the win, Indianapolis now holds the tiebreaker over the Arizona Cardinals for first place in the AFC West.
Pagano’s last win over Buffalo was Sept. 27, 2003.
The win snapped Buffalo’s five-game losing streak in Buffalo.
The Bills were without their starting quarterback Ryan Fitzpatrick (groin), who missed a game after the game because of a hamstring injury.
New England Patriots tight end Rob Gronkowski also was out with a hamstring issue.
The Colts have now won five consecutive games against the Bills, the longest active streak in NFL history.
Pagans team-high 31 points on the ground and 28 points on special teams came against a Bills defense that surrendered just 10 points.
They allowed only a touchdown on the day, and had a sack and interception on their way to scoring on just two possessions in the first quarter.
Bills head coach Doug Marrone said he was pleased with his team’s effort on offense.
“It was just great to see how much the team’s gotten better, getting better, and I’m really proud of the way they’ve come out tonight,” Marrone told reporters after the win.
Buffalo (7-5) lost its fourth straight game, which includes a loss to the Denver Broncos on Saturday. “
We’ve just got to continue to play the way we’ve played and it will pay off when we get to Sunday.”
Buffalo (7-5) lost its fourth straight game, which includes a loss to the Denver Broncos on Saturday.
The team’s last victory came Dec. 12, 2002.
The Sabres (5-7) fell to 2-5 on the season after a 34-28 loss to Houston.
They fell to 1-3 since then.
Marrone had to settle for a 4-3 overtime loss to Buffalo on Sunday because of the injury to rookie running back Matt Forte.
Buffalo has won six of seven overall after taking the field without Forte because of an illness.